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Job Description
In June 2019, Vertex announced the establishment of a new research site in the Boston area where research, development, and clinical manufacturing for cell and genetic therapies will be primarily based. Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat-and even cure-several of the diseases Vertex is focused on, including sickle cell disease, Duchenne muscular dystrophy and type 1 diabetes. Further investment in a research site specifically designed to advance these programs will be key to Vertex's continued and sustained leadership in these exciting approaches. At Vertex Cell and Genetic Therapies (VCGT) our research teams will bring together the best biology, technologies and enhanced manufacturing capabilities to ensure we bring these cutting-edge transformative therapies to patients as quickly as possible.
KEY RESPONSIBILITIES
- Perform in vitro, ex vivo and in vivo studies to investigate the effects of CRISPR-based gene editing on gene and protein expression, cellular readouts and muscle function.
- Develop cutting-edge CRISPR-based technology platforms for research and therapeutic applications.
- Conduct experiments using state-of-the-art molecular and cell biology techniques.
- Establish and culture mammalian cell lines.
- Effectively collaborate with a fully integrated research team to facilitate the success of projects.
- Additional duties and responsibilities as required.
REQUIREMENTS
- Bachelor's or Master's degree in biochemistry, molecular, cellular and in vivo biology, or related discipline with Master's and 4+ years experience or Bachelor's and 6+ years experience.
- Extensive hands-on experience in in vitro techniques, assay development and data analysis.
- Previous experience with CRISPR gene editing is a plus.
- Excellent communication skills with ability to build open and collaborative relationships and work effectively as a member of a multidisciplinary team.
- Excellent organizational skills and documentation practices.
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Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Human Resources at ApplicationAssistance@vrtx.com.